2008
Rohrbach S, Teichert S, Niemann B, Franke C, Katschinski DM (2008) Caloric restriction counteracts age-dependent changes in prolyl-4-hydroxylase domain (PHD) 3 expression. BIOGERONTOLOGY, 2008 Jun; 9(3):169-76.
Teichert S, Rutherford JC, Wottawa M, Heitman J, Tudzynski B (2008) Impact of ammonium permeases mepA, mepB, and mepC on nitrogen-regulated secondary metabolism in Fusarium fujikuroi. Eukaryot Cell, 7(2): 187-201.
Seifert A, Katschinski DM, Tonack S, Fischer B, Navarrete Santos A (2008) Significance of Prolyl Hydroxylase 2 in the Interference of Aryl Hydrocarbon Receptor and Hypoxia-Inducible Factor-1alpha Signaling. CHEM RES TOXICOL, 21(2): 341-8.
2007
Ameri K, Hammond EM, Culmsee C, Raida M, Katschinski DM, Wenger RH, Wagner E, Davis RJ, Hai T, Denko N, Harris AL (2007) Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway. ONCOGENE, 26(2): 284-9.
Barth S, Nesper J, Hasgall PA, Wirthner R, Nytko KJ, Edlich F, Katschinski DM, Stiehl DP, Wenger RH, Camenisch G (2007) The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability. MOL CELL BIOL, 27(10): 3758-68.
Eckhardt K, Troger J, Reissmann J, Katschinski DM, Wagner KF, Stengel P, Paasch U, Hunziker P, Borter E, Barth S, Schlafli P, Spielmann P, Stiehl DP, Camenisch G, Wenger RH (2007) Male germ cell expression of the PAS domain kinase PASKIN and its novel target eukaryotic translation elongation factor eEF1A1. CELL PHYSIOL BIOCHEM, 20(1-4): 227-40.
Köditz J, Nesper J, Wottawa M, Stiehl DP, Camenisch G, Franke C, Myllyharju J, Wenger RH, Katschinski DM (2007) Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor. BLOOD, 110(10): 3610-7.
Valerius O, Kleinschmidt M, Rachfall N, Schulze F, López Marín S, Hoppert M, Streckfuss-Bömeke K, Fischer C, Braus GH (2007) The Saccharomyces homolog of mammalian RACK1, Cpc2/Asc1p, is required for FLO11 dependent adhesive growth and dimorphism. MOL CELL PROTEOMICS, 6 (11): 1968-1979.
Wirthner R, Balamurugan K, Stiehl DP, Barth S, Spielmann P, Oehme F, Flamme I, Katschinski DM, Wenger RH, Camenisch G (2007) Determination and modulation of prolyl-4-hydroxylase domain oxygen sensor activity. METHOD ENZYMOL, 435: 43-60.
2006
Hägele S, Behnam B, Borter E, Wolfe J, Paasch U, Lukashev D, Sitkovsky M, Wenger RH, Katschinski DM (2006) TSGA10 prevents nuclear localization of the hypoxia-inducible factor (HIF)-1alpha. FEBS LETT, 580(15): 3731-8.
Katschinski DM (2006) Is there a molecular connection between hypoxia and aging? EXP GERONTOL, 41(5): 482-4.
Kleinschmidt M, Schulz R, Braus GH (2006) The yeast CPC2/ASC1 gene is regulated by the transcription factors Fhl1p and Ifh1p. CURR GENET, 49 (4): 218-228.
Leich F, Köditz J, Ulbrich-Hofman R, Arnold U (2006) Tandemization endows bovine pancreatic ribonuclease with cytotoxic activity. J MOL BIOL, 358(5): 1305-13.
Stiehl DP, Wirthner R, Köditz J, Spielmann P, Camenisch G, Wenger RH (2006) Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system. J BIOL CHEM, 281(33): 23482-91.
Strittmatter AW, Fischer C, Kleinschmidt M, Braus GH (2006) FLO11 mediated filamentous growth of the yeast Saccharomyces cerevisiae depends on the expression of the ribosomal RPS26 genes. MOL GENET GENOMICS, 276 (2): 113-125.
Teichert S, Wottawa M, Schönig B, Tudzynski B (2006) Role of the Fusarium fujikuroi TOR kinase in nitrogen regulation and secondary metabolism. EUKARYOT CELL, 5(10): 1807-19.
Hägele S, Behnam B, Borter E, Wolfe J, Paasch U, Lukashev D, Sitkovsky M, Wenger RH, Katschinski DM. TSGA10 prevents nuclear localization of the Hypoxia-inducible factor (HIF)-1α (2006). FEBS Lett 580: 3731-3738.
Ameri K, Hammond EM, Culmsee C, Raida M, Katschinski DM, Wenger RH, Wagner E, Davis RJ, Hai T, Denko N, Harris AL. Induction of activating transcription factor 3 (ATF3) by anoxia is independent of p53 and the hypoxic HIF signalling pathway. Oncogene advance online publication 17 July 2006; doi: 10.1038/sj.onc.1209781.
Stiehl DP, Wirthner R, Koditz J, Spielmann P, Camenisch G, Wenger RH (2006). Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system. J Biol Chem 18:23482-23491.
2005
Rohrbach S, Simm A, Pregla R, Franke C, Katschinski DM (2005). Age dependent increase of HIF-α -prolyl-4-hydroxylase (PHD) 3 expression in murine and human heart. Biogerontology 6: 165-171.
Martin F, Linden T, Katschinski DM, Oehme F, Flamme I, Mukhopadhyay CK, Eckhardt K, Tröger J, Barth S, Camenisch G, Wenger RH (2005). Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation. Blood 105: 4613-4619.
Ibrahim NO, Hahn T, Franke C, Stiehl DP, Wirthner R, Wenger RH, Katschinski DM (2005). Induction of the HIF system by low levels of HSP90 inhibitors. Cancer Res 65: 11094-1110.
2004
Katschinski D M, Le L, Schindler SG, Thomas T, Voss AK, Wenger RH (2004) Interaction of the PAS B domain with HSP90 accelerates Hypoxia-Inducible Factor-1α stabilization. Cell Physiol and Biochem 14: 351-360.
Depping R, Hägele S, Wagner KF, Wiesner RJ, Camenisch G, Wenger RH, Katschinski DM (2004) A dominant-negative isoform of the hypoxia inducible factor-1a is specifically expressed in human testis. Biol Reprod 71: 331-339.
Hellwig-Bürgel T, Stiehl DP, Katschinski DM, Marxsen J, Kreft B, Jelkmann W (2004) VEGF production by primary renal proximal tubular cells: requirement fo HIF-1, PI3kinase and MAPKK-1 signaling. Cell Physiol and Biochem 15: 99-108.
2003
Linden, T, Katschinski, DM, Eckhardt, K, Scheid, A, Pagel, H, Wenger RH (2003) The anti-mycotic ciclopirox olamine induces HIF-1 stability, VEGF expression and angiogenesis. FASEB J 17:761-763, 2003.
Unruh A, Ressel A, Mohamed H, Nadrowitz R, Richter E, Johnson RS, Katschinski DM*, Wenger RH* (2003) The hypoxia-inducible factor-1α is a negative factor for tumor therapy. Oncogene 22:3213-3220, 2003. * both authors contributed equally to the work.
Shibata J, Hasegawa J, Siemens A, Wolber E, Dibbelt L, Li D, Katschinski DM, Jelkmann W, Wenger RH, Wagner KF (2003) Hemostasis and coagulation at a hematocrit of 0.85: functional consequences of erythrocytosis. Blood 101:4416-4422, 2003.
Westermann AM, Wiedemann GJ, Jäger E, Jager D, Katschinski DM, Knuth A, Vorde Sive Vording PZ, Van Dijk JD, Finet J, Neumann A, Longo W, Bakshandeh A, Tiggelaar CL, Gillis W, Bailey H, Peters SO, Robins HI (2003) A Systemic Hyperthermia Oncologic Working Group trial. Ifosfamide, carboplatin, and etoposide combined with 41.8 degrees C whole-body hyperthermia for metastatic soft tissue sarcoma. Oncology 64:312-21, 2003.
Katschinski DM, Marti HH, Wagner KF, Shibata J, Eckhardt K, Martin F, Depping R, Paasch U, Gassmann M, Ledermann B, Desbaillets I, Wenger RH (2003) Targeted disruption of of the mouse PAS domain serin/threonine kinase PASKIN. Mol Cell Biol 23:6780-6789.
Hofbauer KH, Gess B, Lohaus C, Meyer HE, Katschinski DM, Kurtz A (2003) Oxygen tension regulates the expression of a group of procollagen hydroxylases. Eur J Biochem 270: 4515-4533.
before 2003
Aga E, Katschinski DM, Laufs H, van Zandbergen G, Hansen B, Müller K, Solbach W, Laskay T (2002) Inhibition of the spontaneous apoptosis of neutrophil granulocytes by the intracellular parasite Leishmania major. J Immunol 169: 898-905.
Katschinski DM, Le L, Wagner K, Schindler SG, Wenger RH (2002) Heat induction of the unphosphorylated form of hypoxia-inducible factor-1α is dependent on heat shock protein-90 activity. J Biol Chem 15: 9262-9267.
Marti* HH, Katschinski* DM, Wagner KF, Schäffer L, Stier B, Wenger RH (2002). Isoform-specific expression of hypoxia-inducible factor-1α during the late stages of mouse spermiogenesis. Mol Endocrinology 16: 234-243.*both authors contributed equally to the work.
Hofer T, Spielmann P, Stengel P, Stier B, Katschinski DM, Desbaillets I, Gassmann M, Wenger RH (2001) Cloning of PASKIN, a mammalian PAS-serin/Threonine kinase protein related to bacterial oxygen sensors. Biochem Biophys Res Com 288: 757-764.
Westermann AM, Grosen EA, Katschinski DM, Jäger D, Rietbrock R, Schink J, Tiggelaar CL, Jäger E, Zum Vorde sive Vording L, Neuman A, Knuth A , van Dijk JDP, Wiedemann GJ, Robins HI (2001). A pilot study of whole body hyperthermia and carboplatin in platinum resistant ovarian cancer. Eur J Cancer 37: 1111-1117.
Katschinski DM, Jacobson EL, Robins HI (2001) Modulation of VP-16 cytotoxicity by carboplatin and 41.8°C hyperthermia. J Cancer Res Clin Oncol 127:425-432.
Wagner K F, Katschinski DM, Hasegawa J, Schumacher D, Meller B, Gembruch U, Schramm U, Jelkmann W, Gassmann M, Fandrey J (2001) Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin. Blood 97: 536-542.
Katschinski DM, Boos K, Schindler SG, Fandrey J (2000) Pivotal role of reactive oxygen species as intracellular mediators of hyperthermia induced apoptosis. J Biol Chem 28: 21094-21098.
Robins HI, Tutsch K, Katschinski DM, Jacobson E, Mehta M, Olsen M, Cohen JD, Tiggelaar CL, Arzoomanian RZ, Alberti D, Feierabend C, Wilding G (1999) A phase I trial of intravenous thymidine and carboplatin in patients with advanced cancer. J Clin Oncol 17: 2922-2931.
Robins HI, Katschinski DM, Longo W, Grosen E, Wilding G, Gillis W, Kraemer CL, Tiggelaar CL, Rushing D, Stewart JA, Spriggs D, Love R, Arzoomanian RZ, Feierabend C, Alberti D, Morgan K, Simon K, d`Oleire F (1999) A pilot study of melphalan, tumor necrosis factor-a and 41.8oC whole body hyperthermia. Cancer Chemoth Pharm 43: 409-414.
Robins HI, Grosen E, Katschinski DM, Longo W, Tiggelaar CL, Kutz M, Winawer J, Graziano F (1999) Whole body hyperthermia induction of soluble tumor necrosis factor receptors: implications for rheumatoid diseases. J Rheumatol 26: 2513-2516.
Katschinski DM, Robins HI, Schad M, Frede S, Fandrey J (1999) Role of TNFa in hyperthermia induced apoptosis of human leukemia cells. Cancer Res 59: 3404-3410.
Katschinski DM, Robins HI (1999) Hyperthermic modulation of SN-38 cleavable complex formation and cytotoxicity through altered topoisomerase I activity. Int J Cancer 80:104-109.
Katschinski DM, Benndorf R, Wiedemann GJ, Mulkerin D, Touhidi R, Robins HI (1999) Heat shock protein antibodies in sarcoma patients undergoing 41.8°C whole body hyperthermia. J Immunother 22: 67-70.
Wiedemann GJ, Robins HI, Katschinski DM, Mentzel M, d`Oleire F, Kutz M, Wagner T (1997) Systemic hyperthermia and ICE chemotherapy for sarcoma patients: rationale and clinical status. Anticancer Res 17: 2899-2902.
Rietbroek RC, Katschinski DM, Reijers MHE, Robins HI, Geerdink A, Tutsch K, d’Oleire F, Havemann J (1997) Lack of thermal enhancement of taxanes in vitro. Int J Hyperthermia 13: 525-533.
Kutz ME, Mulkerin DL, Wiedemann GJ, Katschinski DM, Robins HI (1997) In vitro studies of the hyperthermic enhancement of activated ifosfamide (4-hydroxyperoxy-ifosfamide) and glucose isophophoramide. Cancer Chemoth Pharm 40: 167-171.
Katschinski DM, Wiedemann GJ, Mentzel M, Mulkerin D, Robins HI (1997) Influence of circadian rhythm on 41.8°C whole body hyperthermia induction of hematopoietic growth factors. Int J Hyperthermia 13: 571-576.
Katschinski DM, Wiedemann GJ, Mentzel M, Mulkerin DL, Robins HI (1997) Optimization of chemotherapy administration for clinical 41.8°C whole body hyperthermia. Cancer Letts 115: 195-199.
Katschinski DM, Jelkmann W, Touhidi R, Mentzel M, Mulkerin D, Wiedemann GJ, Robins HI (1997) Dynamic changes in serum erythropoietin levels in solid tumor patients undergoing 41.8oC whole body hyperthermia and/or chemotherapy. Int J Hyperthermia 13: 563-569.
Heits F, Katschinski DM, Wilmsen U, Wiedemann GJ, Jelkmann W (1997) Serum immunoreactive thrombopoietin levels in tumor patients and response to chemotherapy-induced thrombocytopenia. Eur J Haematol 59: 53-58.
Heits F, Katschinski DM, Wiedemann GJ, Weiss C, Jelkmann W (1997) Serum vascular endothelial growth factor (VEGF), a prognostic indicator in sarcoma and carcinoma patients. Int J Oncol 10: 333-337.
Feyerabend T, Steeves R, Jaeger B, Wiedemann GJ, Sommer K, Richter E, Katschinski DM, Robins HI (1997) Local hyperthermia, hyperfractionated radiation, and cisplatin in preirradiated recurrent head and neck cancer. Int J Oncol 10: 591-595.
Wiedemann GJ, Robins HI, Gutsche S, Mentzel M, Katschinski DM, Deeken M, Eleftheriadis S, Crahé R, Weiss C, Storer B, Wagner T (1996) Ifosfamide, Carboplatin and Etoposide (1) combined with 41.8oC whole-body hyperthermia. Eur J Cancer 32 A: 888-892.
Robins HI, Kutz M, Wiedemann GJ, Katschinski DM, Devchand P, Grosen E, Tiggelaar CL, Spriggs D, Gillis W, d`Oleire F (1995) Cytokine induction by 41.8oC whole body hyperthermia. Cancer Letts 97: 195-201.
Kekow J, Wiedemann GJ, Katschinski DM, Kisro J, Geisler J, Wagner T, Szymkoviak C (1995) Whole body hyperthermia increases plasma levels of transforming growth factor b. Int J Oncol 7: 1427-1432.
Katschinski DM, Neustock P, Klüter H, Kirchner H (1994) Influence of various factors on Interferon-a production in cultures of human leukocytes. J Interf Cytok Res 14: 105-110.